Here’s a summary of the latest findings on a common back‑pain drug and dementia risk, based on a large new study:
🧠 Key Finding: Link Between a Pain Drug and Dementia
- A large observational medical records study found that adults prescribed gabapentin (a drug often used for lower back pain and nerve pain) multiple times had a higher risk of dementia and mild cognitive impairment (MCI) later on. (News-Medical)
- Specifically:
- People with six or more prescriptions were ~29 % more likely to be diagnosed with dementia compared with similar patients not prescribed gabapentin. (News-Medical)
- The same group had ~85 % higher risk of MCI (mild cognitive impairment). (News-Medical)
- Higher frequency of prescriptions (e.g., 12 or more) was linked to even greater risk. (News-Medical)
- These increased risks were seen not only in older adults but also in younger adults (35–64)—who doubled their risk of dementia or MCI compared to those who didn’t use the drug. (NAMD)
📌 Important Context
- This was an observational study, meaning it finds an association not proof that gabapentin causes dementia. Other factors (like the pain condition itself) could contribute. (News-Medical)
- Chronic pain itself has also been linked to a higher risk of dementia in some cohort studies—even independent of medication. (Springer)
🩺 What Patients and Doctors Might Do
- Discuss risks with your doctor: If you’re on gabapentin for back pain or nerve pain, talk about the latest findings before making changes.
- Monitor cognitive symptoms: Any memory changes, confusion, or trouble concentrating should be reported to a clinician promptly.
- Consider alternatives: In some cases, other pain management strategies (physical therapy, lifestyle changes, other medications) may be appropriate—but only under medical guidance.
🧠 Bottom Line
A widely prescribed drug for back pain — gabapentin — has been linked in a large study to a higher likelihood of later dementia or mild cognitive impairment, especially with long‑term or frequent use. But this does not prove cause and should be interpreted alongside other health factors and under professional advice. (NAMD)
Would you like me to break down what this might mean for someone currently taking gabapentin? (E.g., practical steps or questions to ask your doctor.)
